Name |
Human NPM1 protein
|
Supplier |
Biorbyt
|
Catalog |
orb168940
|
Category |
Protein
|
Prices |
$230.00, $442.00
|
Sizes |
5 μg, 20 μg
|
Applications |
SDS-PAGE
|
Species Reactivities |
Human
|
Nature |
Recombinant
|
Source |
E. coli
|
Purity |
> 85.0% as determined by SDS-PAGE.
|
Gene |
NPM1
|
Sequence |
MGSSHHHHHH SSGLVPRGSH MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAADEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAK MQASIEKGGS LPKVEAKFIN YVKNCFRMTD QEAIQDLWQW RKSL.
|
Description |
Nucleophosmin Human Recombinant protein. Nucleophosmin (NPM1) is a phosphoprotein which shuffles between the nucleus and the cytoplasm. NPM1 is assumed to be involved in a number of processes including regulation of the ARF/p53 pathway. Several genes fusion partners have been described, particularly the anaplastic lymphoma kinase gene on chromosome 2. NPM1 gene mutations are linked with acute myeloid leukemia.
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Supplier Page |
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