| Name |
Human MANF protein
|
| Supplier |
Biorbyt
|
| Catalog |
orb107776
|
| Category |
Protein
|
| Prices |
$264.00, $357.00, $629.00, $1,046.00, $1,751.00, $2,865.00
|
| Sizes |
5 μg, 25 μg, 100 μg, 250 μg, 500 μg, 1 mg
|
| Applications |
SDS-PAGE HPLC
|
| Species Reactivities |
Human
|
| Nature |
Recombinant
|
| Source |
E.coli
|
| Purity |
> 95% by SDS-PAGE and HPLC analyses.
|
| Gene |
MANF
|
| Sequence |
LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDAATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKILDDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL
|
| Description |
Mesencephalic astrocyte-derived neurotrophic factor, also known as Protein ARMET, Arginine-rich protein, MANF andARMET, is a secreted protein which belongs to the ARMET family. Recombinant human MANF produced by E. coli is a singlepolypeptide chain containing 183 amino acids (25-182) and having a molecular mass of 20.8kDa. MANF reduces endoplasmicreticulum (ER) stress and has neurotrophic effects on dopaminergic neurons. MANF has been described as a survival factor fordopaminergic neurons. MANF expression was widespread in the nervous system and non-neuronal tissues. Mature humanMANF is 99%, 98% and 96% a.a. identical to mature rat, mouse and bovine MANF respectively
|
| Supplier Page |
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|
SDS-PAGE analysis of Human MANF protein