Murine TECK protein

• Supplier: Biorbyt
• Catalog: orb107807
• Category: Protein
• Prices: $221.00, $357.00, $553.00, $910.00
• Sizes: 5 μg, 20 μg, 100 μg, 250 μg
• Applications: SDS-PAGE HPLC
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: E.coli
• Purity: > 95% by SDS-PAGE and HPLC analyses.
• Gene: CCL25
• Sequence: QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVCGNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNSTSVRSATLGHP RMVMMPRKTN N
• Description: Thymus Expressed Chemokine (TECK)/CCL25 is a novel CC chemokine that is distantly related (approximately 20% aminoacid sequence identity) to other CC chemokines. Mouse CCL25 cDNA has also been cloned and shown to encode a 144 aaprotein that exhibits 49% aa sequence identity to human CCL25. The expresssion of human and mouse CCL25 was shown to behighly restricted to the thymus and small intestine. Although dendritic cells have been demonstrated to be the source of CCL25production in the thymus, dendritic cells derived from bone marrow do not express CCL25. Recombinant human and mouseCCL25 have been shown to be chemotactic for activated macrophages, dendritic cells and thymocytes. CCL25 signals throughthe CCR9 receptor.