Murine GMF beta protein

• Supplier: Biorbyt
• Catalog: orb82615
• Category: Protein
• Prices: $221.00, $357.00, $689.00, $1,165.00
• Sizes: 2 μg, 10 μg, 100 μg, 250 μg
• Applications: SDS-PAGE HPLC FA
• Species Reactivities: Mouse
• Source: E.coli
• Purity: >97% pure by SDS-PAGE and HPLC analyses.
• Bioactivity: Less than 1EU/μg of rMuGMF beta as determined by LAL method.
• Gene: GMFB
• Sequence: SESLVVCDVA EDLVEKLRKF RFRKETHNAA IIMKIDKDER LVVLDEELEG VSPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H
• Description: Glia maturation factor beta(GMF beta) coded by GMFb gene at chromosome 14 in mouse, is identical to human GMF beta, with the exception of two amino acid residues. It is a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family, and plays an important role in the upstream regulation of excessive production and the releasing of proinflammatory cytokines/chemokines in brain cells, leading to the destruction of oligodendrocytes, the myelin forming cells, and neurons. Less than 1EU/μg of rMuGMF beta as determined by LAL method.