Name | Rat IL-1 beta protein |
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Supplier | Biorbyt |
Catalog | orb180532 |
Category | Protein |
Prices | $391.00 |
Sizes | 10 μg |
Applications | SDS-PAGE HPLC |
Species Reactivities | Rat |
Source | E. coli |
Purity | > 95.0% |
Bioactivity | The ED50 range= 0.2-0.5 ng/ml, determined by the dose dependent proliferation of mouse D10S cells. |
Gene | Il1b |
Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Val-Pro-Ile-Arg |
Description | Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
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