Recombinant Human Notum Protein, CF
| Name | Recombinant Human Notum Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 9118-NM |
| Category | Protein |
| Prices | $369.00 |
| Sizes | 50 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | Chinese Hamster Ovary cell line, CHO-derived Ser81-Thr451 (Cys330Ser) with a C-terminal 6-His tag |
| Purity | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
| Bioactivity | Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. The ED 50 for this effect is 0.1-0.6 μg/mL in the presence of 0.5 μg/mL of Recombinant Human Wnt-3a (Catalog # 5036-WN ). |
| Endotoxin | <0.10 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | Q6P988 |
| Gene | NOTUM |
| Sequence | Ser81 |
| Supplier Page | Shop |
Product images
Recombinant Human Wnt-3a shows a dose responsive increase in Wnt reporter activity in HEK293 cells (green line). Recombinant Human Notum (Catalog # 9118-NM) inhibits a constant dose of 0.5 μg/mL Recombinant Human Wnt-3a (Catalog # 5036-WN). The ED 50 is typically 0.1-0.6 µg/mL (orange line).