| Name | DHFR |
|---|---|
| Supplier | Nordic BioSite |
| Catalog | PAT-80952-2 |
| Category | Protein |
| Applications | Immunoelectrophoresis |
| Species Reactivities | Mouse |
| Source | References: Chen MJ., et al. (1984) J Biol Chem. 259(6):3933-43. Cody V., et al. (2009) Biochemistry. 48(8):1702-11. |
| Purity | > 95% by SDS - PAGE |
| Bioactivity | Specific activity is > 2000 pmol/min/ug, and is defined as the amount of enzyme that converts 1.0 pmole of dihydrofolic acid to tetrahydrofolic acid per minute at pH 6.5 at 25C. |
| Gene | Dhfr |
| Sequence | MGSSHHHHHH SSGLVPRGSH MVRPLNCIVA VSQNMGIGKN GDLPWPPLRN EFKYFQRMTT TSSVEGKQNL VIMGRKTWFS IPEKNRPLKD RINIVLSREL KEPPRGAHFL AKSLDDALRL IEQPELASKV DMVWIVGGSS VYQEAMNQPG HLRLFVTRIM QEFESDTFFP EIDLGKYKLL PEYPGVLSEV QEEKGIKYKF EVYEKKD |
| Description | Dihydrofolate reductase (DHFR) is a member of the reductase family of enzymes that is ubiquitously expressed in all organisms |
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