Active human MEK1 (mutated S218 + S222) full length protein

• Supplier: Abcam
• Catalog: ab90031
• Category: Protein
• Prices: $445.00
• Sizes: 10 µg
• Applications: SDS-PAGE FA
• Species Reactivities: Human
• Nature: Recombinant
• Source: E. coli
• Purity: > 90 % by SDS-PAGE. ab90031 is purified by gluthatione sepharose and gel filtration.
• Bioactivity: Activity: > 250.000 U/mg (1 Unit is defined as the amount of MEK1 which activates unactive ERK1 (0.3 mg/ml) by 1 U/min using 100 µM ATP at 30°C. 1 U ERK1 activity is defined as 1 pmol phosphate transferred to myelin basic protein (0.2 mg/ml) per min using 125 µM ATP at 30°C).
• SwissProt/Accession: Q02750
• Gene: MAP2K1
• Sequence: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. Contains 1 protein kinase domain.