Active human TGF beta 1 protein

• Supplier: Abcam
• Catalog: ab50036
• Category: Protein
• Prices: $110.00, $257.00
• Sizes: 2 µg, 10 µg
• Applications: SDS-PAGE FA WB
• Species Reactivities: Human
• Nature: Recombinant
• Source: HEK 293 cells
• Purity: > 95 % by SDS-PAGE. Greater than 98% by SDS-PAGE and HPLC analyses.
• Bioactivity: The ED50 was determined by TGF-beta1's ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is = 0.05 ng/ml, corresponding to a specific activity of = 2 x 107 units/mg.
• Endotoxin: < 0.100 Eu/µg
• SwissProt/Accession: P01137
• Gene: TGFB1
• Residue: 279 to 390
• Sequence: ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS

Product References

Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils - Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils

Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y. J Immunol. 2007 Apr 1;178(7):4466-72.

FcepsilonRI aggregation promotes survival of connective tissue-like mast cells - FcepsilonRI aggregation promotes survival of connective tissue-like mast cells

Ekoff M, Strasser A, Nilsson G. J Immunol. 2007 Apr 1;178(7):4177-83.

Stat3 and Stat4 direct development of IL-17-secreting Th cells. - Stat3 and Stat4 direct development of IL-17-secreting Th cells.

Mathur AN, Chang HC, Zisoulis DG, Stritesky GL, Yu Q, O'Malley JT, Kapur R, Levy DE, Kansas GS, Kaplan MH. J Immunol. 2007 Apr 15;178(8):4901-7.

TGFbeta promotes conversion of CD16+ peripheral blood NK cells into CD16- NK - TGFbeta promotes conversion of CD16+ peripheral blood NK cells into CD16- NK

Keskin DB, Allan DS, Rybalov B, Andzelm MM, Stern JN, Kopcow HD, Koopman LA, Strominger JL. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3378-83. Epub 2007 Feb 20.

Notch signaling is necessary for epithelial growth arrest by TGF-beta. - Notch signaling is necessary for epithelial growth arrest by TGF-beta.

Niimi H, Pardali K, Vanlandewijck M, Heldin CH, Moustakas A. J Cell Biol. 2007 Feb 26;176(5):695-707.