FAM84B, 1-310aa, Human, His tag, E.coli

Name FAM84B, 1-310aa, Human, His tag, E.coli
Supplier ARP American Research Products
Catalog 01-P2442
Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Applications SDS-PAGE
Species Reactivities Human
Nature Recombinant
Purity > 85% by SDS - PAGE
Gene FAM84B
Sequence MGSSHHHHHH SSGLVPRGSH MGSMGNQVEK LTHLSYKEVP TADPTGVDRD DGPRIGVSYI FSNDDEDVEP QPPPQGPDGG GLPDGGDGPP PPQPQPYDPR LHEVECSVFY RDECIYQKSF APGSAALSTY TPENLLNKCK PGDLVEFVSQ AQYPHWAVYV GNFQVVHLHR LEVINSFLTD ASQGRRGRVV NDLYRYKPLS SSAVVRNALA HVGAKERELS WRNSESFAAW CRYGKREFKI GGELRIGKQP YRLQIQLSAQ RSHTLEFQSL EDLIMEKRRN DQIGRAAVLQ ELATHLHPAE PEEGDSNVAR TTPPPGRPPA PSSEEEDGEA VAH
Description FAM84B, as known as Family with sequence similarity 84, member B, coprecipitated with a downstream effector of RAS, CRAF. Binding of FAM83B with CRAF disrupted CRAF/14-3-3 interactions and increased CRAF membrane localization, resulting in elevated MAPK and mammalian target of rapamycin (mTOR) signaling
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