| Name | Rat MIP-1 alpha |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 600380 |
| Category | Protein |
| Prices | $250.00 |
| Sizes | 20 µg |
| Species Reactivities | Rat |
| Nature | Recombinant |
| Source | E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug. |
| Purity | Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
| Bioactivity | The activity is determined by the ability to chemoattract human PBMCs at 1-10 ng/mL. Specific activity: 1 x 10e6 units/mg |
| Gene | Ccl3 |
| Sequence | APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA |
| Description | Macrophage Inflammatory Protein-1 alpha (MIP-1alpha), also known as CCL3, is produced by macrophages and is thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1alpha can exist as a naturally occurring heterodimer with MIP-1beta and has been shown to have antiviral activity against HSV-1. Rat MIP-1 alpha is produced in E.coli. Recombinant rat MIP-1 alpha is a non-glycosylated protein, containing 69 amino acids, with a molecular weight of 7.8 kDa. |
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