Rat IL-17F

• Supplier: ABBIOTEC
• Catalog: 600381
• Category: Protein
• Prices: $250.00
• Sizes: 25 µg
• Species Reactivities: Rat
• Nature: Recombinant
• Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
• Purity: Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
• Bioactivity: The activity can be determined by the dose-dependent induction of IL-6 production in cultured mouse NIH 3T3 fibroblasts and is typically 10-20 ng/mL. There is no biological assay data available at this time. Specific activity: 1 x 10e5 units/mg
• Gene: Il17f
• Sequence: MARRNPKVGL SALQKAGNCP PLEDNSVRVD IRIFNQNQGI SVPRDFQNRS SSPWD YNITR DPDRFPSEIA EAQCRHSGCI NAQGQEDGSM NSV PIQQEIL VLRREPQGCS NSFRLEKMLI KVGCTCVTPI VHH AA
• Description: Interleukin 17F (IL-17F) is one of six members of the IL-17 family (IL-17A-F) secreted by activated CD4+ T cells and monocytes. Similar to IL-17A, IL-17F binds to the IL17 RC receptor and promotes the production of IL-6, IL-8, G-CSF and increases matrix turnover rates. IL-17F is also thought to inhibit angiogenesis and induce endothelial cells to produce IL-2, MCP-1 and TGF-beta1. Rat IL-17F is produced in E.coli. Recombinant rat IL-17F is a non-glycosylated, disulfide-linked homodimer, containing two 133 amino acids, with a total molecular weight of 30 kDa.