| Name | Mouse FGF-8 |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 600389 |
| Category | Protein |
| Prices | $250.00 |
| Sizes | 25 µg |
| Species Reactivities | Mouse |
| Source | E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug. |
| Purity | Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard. |
| Bioactivity | The activity is determined by its ability to induce proliferation of mouse 3T3 cells and is typically less than 20 ng/mL. Specific activity: 5 x 10e4 units/mg |
| Gene | Fgf8 |
| Sequence | MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR |
| Description | Fibroblast Growth Factor-8 (FGF-8) has broad functions that involve proliferation, differentiation and cell migration. Inappropriate expression of FGF-8 is linked to increased tumor growth and angiogenesis. There is 100% homology between human and mouse FGF-8. Mouse FGF-8 is produced in E. coli as a non-glycosylated protein containing 194 amino acids, with a total molecular weight of 22.5 kDa. |
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