Name |
Human PSP
|
Supplier |
ABBIOTEC
|
Catalog |
600396
|
Category |
Protein
|
Prices |
$250.00
|
Sizes |
20 µg
|
Species Reactivities |
Human
|
Source |
E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
|
Purity |
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
|
Bioactivity |
The activity is determined by a cell proliferation assay with TT human medullary thyroid cancer cells and is typically 4 - 16 ng/mL. Specific activity: 2.5 x 10e5 units/mg
|
Gene |
PSPN
|
Sequence |
MALSGPCQLW SLTLSVAELG LGYASEEKVI FRYCAGSCPR GARTQHGLAL ARLQGQGRAH GGPCCRPTRY TDVAFLDDRH RWQRLPQLSA AACGCGG
|
Description |
Persephin (PSP) is a neurotrophic factor that promotes survival and growth of dopaminergic and motor neurons, but not peripheral neurons. Human PSP is produced in E. coli as a non-glycosylated, disulfide-linked homodimer, containing two 97 amino acid chains, each with a molecular weight of 10.4 kDa.
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