| Name | Human P-Selectin |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 600291 |
| Category | Protein |
| Prices | $250.00 |
| Sizes | 10 µg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | E. coli |
| Purity | Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA. |
| Gene | SELPLG |
| Sequence | His-Tag sequence not included: EAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFM LRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQ SVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTM TCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIK CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCNNGFKLEGPNNVECTTSGR WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFG CNAGFTLIGDSTLSCRPSGQWTAVTPACRA |
| Description | P-selectin belongs to a family of divalent cation dependent carbohydrate-binding glycoproteins or adhesion molecules. P-selectin is expressed transiently on the surface of activated platelets and endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. Levels of P-selectin may be elevated in a number of pathological conditions. Recombinant human P-selectin comprises a 566 amino acid fragment (197-761) corresponding to the cysteine rich complement control protein domain and is expressed in E. coli with an amino-terminal hexahistidine tag. |
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