Name | SUFU Peptide |
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Supplier | ABBIOTEC |
Catalog | 350501 |
Category | Peptide |
Prices | $50.00 |
Sizes | 100 µg |
Purity | Purity > 80% by HPLC |
Gene | SUFU |
Sequence | The synthetic peptide used to raise the antibody Cat. No. 200139 is selected from a sequence within the C-term region of human SUFU. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
Description | SUFU is a negative regulator in the hedgehog signaling pathway that down-regulates GLI1-mediated transactivation of target genes. Defects in SUFU are a cause of medulloblastoma, a malignant and invasive embryonal tumor of the cerebellum. |
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