PKA Inhibitor [6-22] Peptide

Name PKA Inhibitor [6-22] Peptide
Supplier ABBIOTEC
Catalog 350008
Category Peptide
Prices $139.00
Sizes 1 mg
Purity Purity > 95% by HPLC
Gene PKIA
Sequence Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2 or TYADFIASGRTGRRNAI-NH2
Description This peptide is a potent and competitive inhibitor of protein kinase A (PKA) with a Ki = 1.7 nM. The peptide sequence corresponds to residues 6-22 of human cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) and is amidated at the C-terminus end. PKI-alpha interacts with the catalytic subunit of PKA after the cAMP-induced dissociation of its regulatory chains.
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