Name | CYLD Peptide |
---|---|
Supplier | ABBIOTEC |
Catalog | 350498 |
Category | Peptide |
Prices | $50.00 |
Sizes | 100 µg |
Purity | Purity > 80% by HPLC |
Gene | CYLD |
Sequence | The synthetic peptide used to raise the antibody Cat. No. 200136 is selected from a sequence within the N-term region of human CYLD. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
Description | CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked polyubiquitin chains. Defects in CYLD are the cause of familial cylindromatosis, a highly tumor type-specific disorder. |
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