| Name | APC Peptide |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 350494 |
| Category | Peptide |
| Prices | $50.00 |
| Sizes | 100 µg |
| Purity | Purity > 80% by HPLC |
| Gene | APC |
| Sequence | The synthetic peptide used to raise the antibody Cat. No. 200132 is selected from a sequence within the N-term region of human APC. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| Description | The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members. |
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