Recombinant BRD4 (333-460) protein
| Name | Recombinant BRD4 (333-460) protein |
|---|---|
| Supplier | ActiveMotif |
| Catalog | 31446 |
| Category | Protein |
| Prices | $395.00, $2,600.00 |
| Sizes | 100 μg, 1 mg |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | E. coli |
| Gene | BRD4 |
| Description | The peptide corresponding to amino acids 333-460 that contains the bromodomain sequences of BRD4 (accession number NP_490597.1) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.9 kDa |
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Product images
Recombinant BRD4 (333-460) protein gel. BRD4 (333-460) protein was run on an SDS-PAGE gel and stained with Coomassie blue.
Recombinant BRD4 (333-460) activity using AlphaScreen. BRD4 (333-460) titration and inhibition were assessed using an AlphaScreen® assay. Titration curves were generated to show signal response in the presence of modified peptide substrate at increasing protein concentrations. An IC50 dose response assessment of reference compounds JQ1, I-BET151, Bromosporine and PFI-1 is also shown. This data was generated and kindly provided courtesy of ChemPartner.