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MFHGIP A TPGIG A PGNKP E LY E E VKLYKN A R E R E KYDNM A E LF A VVKTMQ A L E K A YIKDCVSPS E YT A A CSRLLVQYK A A FRQVQGS E ISSID E FCRKFRLDCPL A M E RIK E DRPITIKDDKGNLNRCI A DVVSLFITVMDKLRL E IR A MD E IQPDLR E LM E TMHRMSHLPPDF E GRQTVSQWLQTLSGMS A SD E LDDSQVRQMLFDL E S A YN A FNRFLH A . Introduction: VPS28 is a subunit of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. VPS28 is involved in endosomal sorting of cell surface receptors using a multivesicular body/late endosome pathway. VSP28 binding with the TSG101 may have significant roles in budding of Retroviruses, such as HIV-1 and Ebola virus.VSP28 interacts with TSG101, VPS37B, VPS37C, FAM125A and FAM125B, and also with VPS36, this interaction mediates the association with the ESCRT-II complex. Furthermore it interacts with SNF8 and VPS25 and CEP55.Description: VPS28 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containi
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