Recombinant Human Multiple Coagulation Factor Deficiency 2

• Supplier: Genway Biotech
• Catalog: GWB-B22481
• Category: Protein
• Prices: $75.00, $165.00, $2,685.00
• Sizes: 5 μg, 20 μg, 1000 μg
• Species Reactivities: Human
• Nature: Recombinant
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• SwissProt/Accession: Q8NI22
• Gene: MCFD2
• Sequence: M A SMTGGQQMGRGSHM E E P A A SFSQPGSMGLDKNTVHDQ E HIM E HL E GVINKP E A E MSPQ E LQLHYFKMHDYDGNNLLDGL E LST A ITHVHK E E GS E Q A PLMS E D E LINIIDGVLRDDDKNNDGYIDY A E F A KSLQ. Introduction: The MCFD2-LMAN1 complex forms an explicit cargo receptor for the ER-to-Golgi transport of selected proteins. MCFD2 is involved in the secretion of coagulation factors. MCFD2 is expressed by neural stem/progenitor cells of the hippocampus, and localized to region where neurogenesis persists throughout life. MCFD2 prevents NSC cell death and maintains stem cell characteristics. MCFD2 forms a complex with LAMN1 that facilitates the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus through an endoplasmic reticulum Golgi intermediate compartment. Mutations in the MCFD2 cause Factor V and Factor VIII combined deficiency.Description: MCFD2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 136 amino acids (27-146
• Description: Recombinant Human Multiple Coagulation Factor Deficiency 2