Recombinant Human Glutaredoxin 5

Name Recombinant Human Glutaredoxin 5
Supplier Genway Biotech
Catalog GWB-AF8DF9
Category Protein
Prices $75.00, $165.00, $2,685.00
Sizes 5 μg, 20 μg, 1000 μg
Species Reactivities Human
Nature Recombinant
Purity Greater than 85% as determined by SDS-PAGE.
SwissProt/Accession Q86SX6
Gene GLRX5
Sequence MGSSHHHHHHSSGLVPRGSHMSGSLGR A A A A LLRWGRG A GGGGLWGPGVR A A GSG A GGGGS A E QLD A LVKKDKVVVFLKGTP E QPQCGFSN A VVQILRLHGVRDY A A YNVLDDP E LRQGIKDYSNWPTIPQVYLNG E FVGGCDILLQMHQNGDLV E E LKKLGIHS A LLD E KKDQDSK. Introduction: GLRX5 is small redox enzyme of approximately 100 amino acids which uses glutathione as a cofactor. GLRX5 is a mitochondrial protein, which is evolutionarily conserved. GLRX5 is oxidized by substrates, and reduced non-enzymatically by glutathione. GLRX5 is involved in the biogenesis of iron-sulfur clusters that are required for normal iron homeostasis. GLRX5 is necessary for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1. Defects in the GLRX5 gene are a cause of anemia sideroblastic pyridoxine-refractory autosomal recessive (PRARSA).Description: GLRX5 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 177 amino acids (1-157 a.a.) and having a molecular mass of 18.8 kDa. GRX5 is fused to a 20
Description Recombinant Human Glutaredoxin 5
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