Name |
Recombinant Human NRG4
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Supplier |
Creative Biomart
|
Catalog |
NRG4-525H
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Category |
Protein
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Species Reactivities |
Human
|
Nature |
Recombinant
|
Source |
E. coli
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Purity |
≥96% by SDS-PAGE and HPLC
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Bioactivity |
The ED50 was determined by the phosphorylation of ErbB2 and ErbB4 receptors in CHO cells, and was found to be <3ng/ml, corresponding to a specific activity of 3x 10^5 Units/mg.
|
SwissProt/Accession |
Q8WWG1
|
Gene |
NRG4
|
Sequence |
HEEPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSNLFEAF
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Description |
Recombinant human Neuregulin-4 EGF domain is a disulfide-linked monomeric protein consisting of 62 amino acid residue subunits, and migrates as an approximately 7 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Neuregulin-4 EGF domain was expressed in E. coli.
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