Recombinant Human Nodal Protein, CF

• Supplier: R&D Systems
• Catalog: 3218-ND/CF
• Category: Protein
• Prices: $329.00
• Sizes: 25 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: E. coli -derived His238-Leu347, with an N-terminal Met
• Purity: >97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Bioactivity: Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Yeo, C. et al . (2001) Mol. Cell. 7 :949. Approximately 100 ng/mL of Recombinant Human Nodal can effectively induce Smad2 phosphorylation.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: Q96S42
• Gene: NODAL
• Sequence: Met

Product References

Nodal promotes invasive phenotypes via a mitogen-activated protein - Nodal promotes invasive phenotypes via a mitogen-activated protein

Quail DF, Zhang G, Findlay SD, Hess DA, Postovit LM. Oncogene. 2014 Jan 23;33(4):461-73.

Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and - Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and

Esquivies L, Blackler A, Peran M, Rodriguez-Esteban C, Izpisua Belmonte JC, Booker E, Gray PC, Ahn C, Kwiatkowski W, Choe S. J Biol Chem. 2014 Jan 17;289(3):1788-97.

Nodal.Gdf1 heterodimers with bound prodomains enable serum-independent nodal - Nodal.Gdf1 heterodimers with bound prodomains enable serum-independent nodal

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Widespread potential for growth-factor-driven resistance to anticancer kinase - Widespread potential for growth-factor-driven resistance to anticancer kinase

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Activin a efficiently specifies definitive endoderm from human embryonic stem - Activin a efficiently specifies definitive endoderm from human embryonic stem

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Requirement of glycosylphosphatidylinositol anchor of Cripto-1 for trans activity - Requirement of glycosylphosphatidylinositol anchor of Cripto-1 for trans activity

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