Recombinant Human CD6 Fc Chimera Protein, CF

• Supplier: R&D Systems
• Catalog: 627-CD
• Category: Protein
• Prices: $329.00
• Sizes: 100 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Human CD6 (His18 - Glu398) Accession # Q8WWJ7 DIEGRMD Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by the ability of the immobilized protein to support the adhesion of HuT 78 human cutaneous T cell lymphoma cells. Optimal dilutions should be determined by each laboratory for each application.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: Q8WWJ7
• Gene: CD6
• Sequence: His18

Product References

Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6. - Dynamic coupling of ALCAM to the actin cortex strengthens cell adhesion to CD6.

Te Riet J, Helenius J, Strohmeyer N, Cambi A, Figdor CG, Muller DJ. J Cell Sci. 2014 Apr 1;127(Pt 7):1595-606.

Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular - Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular

Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L. Am J Pathol. 2012 Nov;181(5):1540-59.

Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in - Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in

Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. J Clin Invest. 2006 Oct;116(10):2643-52. Epub 2006 Sep 21.

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation - Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation

Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG. Blood. 2006 Apr 15;107(8):3212-20. Epub 2005 Dec 13.

Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface - Mitogen-activated protein kinase pathway activation by the CD6 lymphocyte surface

Ibanez A, Sarrias MR, Farnos M, Gimferrer I, Serra-Pages C, Vives J, Lozano F. J Immunol. 2006 Jul 15;177(2):1152-9.

Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates - Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates

Fischer M, Harvima IT, Carvalho RF, Moller C, Naukkarinen A, Enblad G, Nilsson G. J Clin Invest. 2006 Oct;116(10):2748-56. Epub 2006 Sep 7.