Recombinant Rat ROBO1 Fc Chimera Protein, CF

• Supplier: R&D Systems
• Catalog: 1749-RB
• Category: Protein
• Prices: $329.00
• Sizes: 50 µg
• Species Reactivities: Rat
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Rat ROBO1 (Lys19-Ile560) Accession # O55005 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Bioactivity: Measured by its binding ability in a functional ELISA. Biotinylated recombinant mouse Slit-3 immobilized on a streptavidin-coated plate at 1 µg/mL can bind Recombinant Rat ROBO1 Fc Chimera with an apparent K d <10 nM.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: O55005
• Gene: Robo1
• Sequence: Lys19

Product References

Axon guidance factor SLIT2 inhibits neural invasion and metastasis in pancreatic - Axon guidance factor SLIT2 inhibits neural invasion and metastasis in pancreatic

Gohrig A, Detjen KM, Hilfenhaus G, Korner JL, Welzel M, Arsenic R, Schmuck R, Bahra M, Wu JY, Wiedenmann B, Fischer C. Cancer Res. 2014 Mar 1;74(5):1529-40.

Robo1 modulates proliferation and neurogenesis in the developing neocortex. - Robo1 modulates proliferation and neurogenesis in the developing neocortex.

Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD. J Neurosci. 2014 Apr 16;34(16):5717-31.

Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic - Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic

Ricano-Cornejo I, Altick AL, Garcia-Pena CM, Nural HF, Echevarria D, Miquelajauregui A, Mastick GS, Varela-Echavarria A. J Neurosci Res. 2011 Oct;89(10):1531-41.

Robo1 regulates semaphorin signaling to guide the migration of cortical - Robo1 regulates semaphorin signaling to guide the migration of cortical

Hernandez-Miranda LR, Cariboni A, Faux C, Ruhrberg C, Cho JH, Cloutier JF, Eickholt BJ, Parnavelas JG, Andrews WD. J Neurosci. 2011 Apr 20;31(16):6174-87.

Angiocrine factors modulate tumor proliferation and motility through EphA2 - Angiocrine factors modulate tumor proliferation and motility through EphA2

Brantley-Sieders DM, Dunaway CM, Rao M, Short S, Hwang Y, Gao Y, Li D, Jiang A, Shyr Y, Wu JY, Chen J. Cancer Res. 2011 Feb 1;71(3):976-87.

Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between - Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between

Dunaway CM, Hwang Y, Lindsley CW, Cook RS, Wu JY, Boothby M, Chen J, Brantley-Sieders DM. Mol Cell Biol. 2011 Feb;31(3):404-16.

The chemorepellent Slit3 promotes monocyte migration. - The chemorepellent Slit3 promotes monocyte migration.

Geutskens SB, Hordijk PL, van Hennik PB. J Immunol. 2010 Dec 15;185(12):7691-8.