Name | Recombinant Human Jagged 2 Fc Chimera Protein, CF |
---|---|
Supplier | R&D Systems |
Catalog | 1726-JG |
Category | Protein |
Prices | $329.00 |
Sizes | 50 µg |
Species Reactivities | Human |
Nature | Recombinant |
Source | Chinese Hamster Ovary cell line, CHO-derived Human Jagged 2 (Met27-Leu1082) Accession #AAB61285 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus |
Purity | >85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Bioactivity | Measured by the ability of the immobilized protein to enhance BMP-2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. Nobta, M. et al . (2005) J. Biol. Chem. 280 :15842. The ED 50 for this effect is 0.5-2 µg/mL. |
Endotoxin | <0.10 EU per 1 μg of the protein by the LAL method. |
SwissProt/Accession | AAB84215 |
Gene | JAG2 |
Sequence | Met27 |
Supplier Page | Shop |
Diaz B, Yuen A, Iizuka S, Higashiyama S, Courtneidge SA. J Cell Biol. 2013 Apr 15;201(2):279-92.
Sundlisaeter E, Edelmann RJ, Hol J, Sponheim J, Kuchler AM, Weiss M, Udalova IA, Midwood KS, Kasprzycka M, Haraldsen G. Am J Pathol. 2012 Sep;181(3):1099-111.
Erceg S, Lukovic D, Moreno-Manzano V, Stojkovic M, Bhattacharya SS. Curr Protoc Stem Cell Biol. 2012 Mar;Chapter 1:Unit 1H.5. doi: