Name | Recombinant Human Crossveinless-2 Protein |
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Supplier | R&D Systems |
Catalog | 1956-CV |
Category | Protein |
Prices | $329.00 |
Sizes | 50 µg |
Species Reactivities | Human |
Nature | Recombinant |
Source | Mouse myeloma cell line, NS0-derived Val34-Asp369, with an N-terminal 7-His tag & Ala39-Asp369 (N-terminal fragments) & Pro370-Arg685 (C-terminal fragment) |
Purity | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Bioactivity | Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al . (2004) Biochem. Biophys. Res. Commun. 315 :272. The ED 50 for this effect is 0.5-2 µg/mL in the presence of 30 ng/mL of Recombinant Human BMP-4 (Catalog # 314-BP ). |
Endotoxin | <0.10 EU per 1 μg of the protein by the LAL method. |
SwissProt/Accession | Q8N8U9 |
Gene | BMPER |
Sequence | His & Ala39 (N-terminal fragments) & Pro370 (C-terminal fragment) |
Supplier Page | Shop |
Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, Robles-Diaz D, Coffee M, Gohring G, Drager G, Potz O, Joos T, Martinez-Hackert E, Haverich A, Buettner FF, Martin U, Zweigerdt R. Nat Commun. 2016 Dec 9;7:13602.
Olsen OE, Wader KF, Misund K, Vatsveen TK, Ro TB, Mylin AK, Turesson I, Stordal BF, Moen SH, Standal T, Waage A, Sundan A, Holien T. Blood Cancer J. 2014 Mar 21;4:e196.
Satomi-Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, Emoto N, Asada Y, Takai Y, Hirata K, Rikitake Y. J Biol Chem. 2012 Aug 31;287(36):30336-45.
Yao Y, Jumabay M, Ly A, Radparvar M, Wang AH, Abdmaulen R, Bostrom KI. Blood. 2012 May 24;119(21):5037-47.
Helbing T, Rothweiler R, Ketterer E, Goetz L, Heinke J, Grundmann S, Duerschmied D, Patterson C, Bode C, Moser M. Blood. 2011 Nov 3;118(18):5040-9.