Recombinant Human Contactin-2/TAG1 Protein, CF

Name	Recombinant Human Contactin-2/TAG1 Protein, CF
Supplier	R&D Systems
Catalog	1714-CN
Category	Protein
Prices	$329.00
Sizes	25 µg
Species Reactivities	Human
Nature	Recombinant
Source	Mouse myeloma cell line, NS0-derived Leu29-Asn1012, with a C-terminal 10-His tag
Purity	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Bioactivity	Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Optimal neurite outgrowth was observed when neurons were plated on 96-well culture plates that had been pre-coated with 50 µL/well of the rhContactin-2 solution at 10-25 µg/mL.
Endotoxin	<0.10 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession	Q02246
Gene	CNTN2
Sequence	Leu29
Supplier Page	Shop

Product References

Neurofascin as target of autoantibodies in Guillain-Barre syndrome. - Neurofascin as target of autoantibodies in Guillain-Barre syndrome.

Pruss H, Schwab JM, Derst C, Gortzen A, Veh RW. Brain. 2011 May;134(Pt 5):e173; author reply e174.

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis - Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis

Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, Kumpfel T, Moldenhauer A, Rader C, Sonderegger P, Pollmann W, Tiefenthaller C, Bauer J, Lassmann H, Wekerle H, Karagogeos D, Hohlfeld R, Linington C, Meinl E. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8302-7. doi:

Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the - Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the

Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel MP, Goureau O, Watanabe K, Goutebroze L, Gaspar P, Zalc B, Karagogeos D, Thomas JL. J Neurosci. 2008 Jul 23;28(30):7624-36.