Recombinant Human Semaphorin 6A Fc Chimera Protein, CF

• Supplier: R&D Systems
• Catalog: 1146-S6
• Category: Protein
• Prices: $329.00
• Sizes: 25 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Human Semaphorin 6A (Gly19-Thr649) Accession # Q9H2E6 DIEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Bioactivity: Measured by its ability to inhibit the proliferation of HUVEC human umbilical vein endothelial cells. Moriya, J. et al . (2010) Circ. Res. 106 :391. The ED 50 for this effect is 0.4-2.4 μg/mL.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: Q9H2E6
• Gene: SEMA6A
• Sequence: Gly19

Product References

Neurotrophin Promotes Neurite Outgrowth by Inhibiting Rif GTPase Activation - Neurotrophin Promotes Neurite Outgrowth by Inhibiting Rif GTPase Activation

Tian X, Yan H, Li J, Wu S, Wang J, Fan L. Int J Mol Sci. 2017 Jan 13;18(1). pii: E148.

Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye - Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye

Ebert AM, Childs SJ, Hehr CL, Cechmanek PB, McFarlane S. Development. 2014 Jun;141(12):2473-82.

Semaphorin 6A regulates angiogenesis by modulating VEGF signaling. - Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.

Segarra M, Ohnuki H, Maric D, Salvucci O, Hou X, Kumar A, Li X, Tosato G. Blood. 2012 Nov 8;120(19):4104-15.

Measles virus modulates dendritic cell/T-cell communication at the level of - Measles virus modulates dendritic cell/T-cell communication at the level of

Tran-Van H, Avota E, Bortlein C, Mueller N, Schneider-Schaulies S. Eur J Immunol. 2011 Jan;41(1):151-63.

Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in - Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in

Renaud J, Kerjan G, Sumita I, Zagar Y, Georget V, Kim D, Fouquet C, Suda K, Sanbo M, Suto F, Ackerman SL, Mitchell KJ, Fujisawa H, Chedotal A. Nat Neurosci. 2008 Apr;11(4):440-9.