Recombinant Mouse Hip Protein

• Supplier: R&D Systems
• Catalog: 1568-HP
• Category: Protein
• Prices: $329.00
• Sizes: 50 µg
• Species Reactivities: Mouse
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Mouse Hip (Lys24 - Arg678 & Asp52 - Arg678) Accession # AAD31172 IEGRMDGGGSGGGSGGGS 10-His tag N-terminus C-terminus
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to inhibit Sonic Hedgehog (Shh) induction of alkaline phosphatase production in C3H10T1/2 mouse embryonic fibroblast cells. The ED 50 for this effect is 1.5-7.5 µg/mL in the presence of 5 µg/mL rmShh.
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: AAD31172
• Gene: Hhip
• Sequence: Lys24 & Asp52

Product References

Stromal cells expressing hedgehog-interacting protein regulate the proliferation - Stromal cells expressing hedgehog-interacting protein regulate the proliferation

Kobune M, Iyama S, Kikuchi S, Horiguchi H, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kamihara Y, Hayashi T, Miyanishi K, Sato Y, Takimoto R, Kato J. Blood Cancer J. 2012 Sep 7;2:e87.

Localization of the human hedgehog-interacting protein (Hip) in the normal and - Localization of the human hedgehog-interacting protein (Hip) in the normal and

Kayed H, Kleeff J, Esposito I, Giese T, Keleg S, Giese N, Buchler MW, Friess H. Mol Carcinog. 2005 Apr;42(4):183-92.