| Name | Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera Protein, CF |
|---|---|
| Supplier | R&D Systems |
| Catalog | 587-RI |
| Category | Protein |
| Prices | $349.00 |
| Sizes | 50 µg |
| Species Reactivities | Mouse |
| Nature | Recombinant |
| Source | Spodoptera frugiperda , Sf 21 (baculovirus)-derived Mouse TGF-beta RI (Ala21-Glu121) & (Thr22-Glu121) Accession # BAA05023 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus |
| Purity | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain |
| Bioactivity | Measured by its binding ability in a functional ELISA. When Recombinant Rat Endoglin/CD105 Fc Chimera (Catalog # 6440-EN ) or Recombinant Mouse Endoglin/CD105 Fc Chimera (Catalog # 1320-EN ) is immobilized at 2 μg/mL (100 μL/well), the concentration of Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 μg/mL. |
| Endotoxin | <0.1 EU per 1 μg of the protein by the LAL method. |
| SwissProt/Accession | BAA05023 |
| Gene | Tgfbr1 |
| Sequence | Ala21 & Thr22 |
| Supplier Page | Shop |
Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV. J Biol Chem. 2011 Aug 26;286(34):30034-46.
Niessen K, Zhang G, Ridgway JB, Chen H, Yan M. Blood. 2010 Feb 25;115(8):1654-61.