Recombinant Human Wnt-5b Protein

• Supplier: R&D Systems
• Catalog: 7347-WN
• Category: Protein
• Prices: $399.00
• Sizes: 25 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Chinese Hamster Ovary cell line, CHO-derived Gln18-Lys359
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Bioactivity: Measured by its ability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3‑E1 mouse preosteoblast cells. The ED 50 for this effect is 125-750 ng/mL, in the presence of 5 ng/mL of Recombinant Mouse Wnt‑3a (Catalog # 1324-WN ). Optimal dilutions should be determined by each laboratory for each application.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: NP_110402
• Gene: WNT5B
• Sequence: Gln18 predicted: No results obtained, sequencing might be blocked

Product References

Tumour cell-derived WNT5B modulates in vitro lymphangiogenesis via induction of - Tumour cell-derived WNT5B modulates in vitro lymphangiogenesis via induction of

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Downregulation of the Canonical WNT Signaling Pathway by TGFbeta1 Inhibits - Downregulation of the Canonical WNT Signaling Pathway by TGFbeta1 Inhibits

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Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced - Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced

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Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling - Assessment of Frizzled 6 membrane mobility by FRAP supports G protein coupling

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Wnt5b promotes the cell motility essential for metastasis of oral squamous cell - Wnt5b promotes the cell motility essential for metastasis of oral squamous cell

Takeshita A, Iwai S, Morita Y, Niki-Yonekawa A, Hamada M, Yura Y. Int J Oncol. 2014 Jan;44(1):59-68.