Recombinant Human Soggy-1/DkkL1 Protein, CF

• Supplier: R&D Systems
• Catalog: 1549-S1/CF
• Category: Protein
• Prices: $329.00
• Sizes: 25 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Ala31-Leu242, with a C-terminal 10-His tag
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its ability to inhibit proliferation of HeLa human cervical epithelial carcinoma cells. The ED 50 for this effect is 2-6 µg/mL.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: Q9UK85.1
• Gene: DKKL1
• Sequence: Ala31

Product References

Widespread potential for growth-factor-driven resistance to anticancer kinase - Widespread potential for growth-factor-driven resistance to anticancer kinase

Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Nature. 2012 Jul 26;487(7408):505-9.

Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients. - Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients.

Zenzmaier C, Marksteiner J, Kiefer A, Berger P, Humpel C. J Neurochem. 2009 Jul;110(2):653-61.