Recombinant Human RGM-B Protein, CF

• Supplier: R&D Systems
• Catalog: 3630-RG
• Category: Protein
• Prices: $329.00
• Sizes: 50 µg
• Species Reactivities: Human
• Nature: Recombinant
• Source: Mouse myeloma cell line, NS0-derived Gly87-Asp209 (N-terminus chain) & Pro210-Ser452 (C-terminus chain), with a C-terminal 6-His tag
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Bioactivity: Measured by its binding ability in a functional ELISA. Immoblized rhBMP-4 at 1 µg/mL (100 µL/well) can bind rhRGM-B with a linear range of 10-500 ng/mL.
• Endotoxin: <0.01 EU per 1 μg of the protein by the LAL method.
• SwissProt/Accession: AAH67736
• Gene: RGMB
• Sequence: Gly87 & Pro210

Product References

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes - RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes

Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco LM, Hua P, Duke-Cohan JS, Umetsu DT, Sharpe AH, DeKruyff RH, Freeman GJ. J Exp Med. 2014 May 5;211(5):943-59.

Repulsive guidance molecule (RGM) family proteins exhibit differential binding - Repulsive guidance molecule (RGM) family proteins exhibit differential binding

Wu Q, Sun CC, Lin HY, Babitt JL. PLoS One. 2012;7(9):e46307.