Name |
Active human ErbB 2 protein fragment
|
Supplier |
Abcam
|
Catalog |
ab182691
|
Category |
Protein
|
Prices |
$372.00
|
Sizes |
50 µg
|
Applications |
SDS-PAGE FA
|
Species Reactivities |
Human
|
Nature |
Recombinant
|
Source |
HEK 293 cells
|
Purity |
>95% by SDS-PAGE .
|
Bioactivity |
Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 Human breast cancer cell proliferation. The ED 50 for this effect is typically 5 - 45 ng/ml in the presence of 0.6 μg/ml goat anti-hErbB 2.
|
Endotoxin |
< 1.000 Eu/µg
|
SwissProt/Accession |
P04626
|
Gene |
ERBB2
|
Residue |
23 to 652
|
Sequence |
TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLS FLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDP LNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDI FHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAG GCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSG ICELHCPA LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQ EVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKI FGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLP DLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHH NTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHC WGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEE GACQPCPINCTHSCVDLDDKGCPAEQRASPLT
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