Active human ErbB 2 protein fragment

Name Active human ErbB 2 protein fragment
Supplier Abcam
Catalog ab182691
Category Protein
Prices $372.00
Sizes 50 µg
Applications SDS-PAGE FA
Species Reactivities Human
Nature Recombinant
Source HEK 293 cells
Purity >95% by SDS-PAGE .
Bioactivity Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 Human breast cancer cell proliferation. The ED 50 for this effect is typically 5 - 45 ng/ml in the presence of 0.6 μg/ml goat anti-hErbB 2.
Endotoxin < 1.000 Eu/µg
SwissProt/Accession P04626
Gene ERBB2
Residue 23 to 652
Sequence TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLS FLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDP LNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDI FHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAG GCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSG ICELHCPA LVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQ EVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKI FGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLP DLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHH NTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHC WGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQ NGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEE GACQPCPINCTHSCVDLDDKGCPAEQRASPLT
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