Active human ErbB 3 protein fragment
| Name | Active human ErbB 3 protein fragment |
|---|---|
| Supplier | Abcam |
| Catalog | ab155696 |
| Category | Protein |
| Prices | $352.00 |
| Sizes | 100 µg |
| Applications | FA SDS-PAGE |
| Species Reactivities | Human |
| Nature | Recombinant |
| Source | HEK 293 cells |
| Tag/Conjugation | His tag C-Terminus |
| Purity | >95% by SDS-PAGE . |
| Bioactivity | Measured by its ability to inhibit the biological activity of Neuregulin1-ß1 on MCF7 Human breast cancer cells. In the presence of 10 ng/ml Recombinant Human NRG1-ß1/HRG1-ß1 Extracellular Domain. The ED 50 for this effect is typically 0.5-3.0 µg/ml. |
| Endotoxin | < 1.000 Eu/µg |
| SwissProt/Accession | P21860 |
| Gene | ERBB3 |
| Residue | 60 to 643 |
| Sequence | SEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTG HNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFV MLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRD RDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCF GPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLT FQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKM CEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLN GDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIG GRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLN WTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLS CRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSG SDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQ GCKGPELQDCLGQTLVLIGKTHLT |
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Product images
SDS-PAGE of reduced ab155696 stained overnight with Coomassie Blue.