C/EBP α Antibody (G-10): sc-166258

C/EBP α Antibody (G-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects C/EBP α in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). C/EBP α (G-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. C/EBP α, a member of the CCAAT/enhancer-binding protein family, plays a crucial role as a transcription factor that regulates gene expression across various tissues, including the liver, adipose tissue, lung, and intestine. C/EBP α is involved in the differentiation of liver and adipose cells, as well as blood cells and the endocrine pancreas, highlighting its importance in metabolic processes and cellular development. C/EBP α′s structure features a basic region/leucine zipper motif that facilitates binding to specific DNA sequences, allowing function in terminally differentiated, growth-arrested cells. In the liver, C/EBP α acts as a transactivator for several genes regulated by growth hormone, which increases C/EBP α mRNA and protein levels while enhancing DNA-binding activity. This regulatory mechanism underscores C/EBP α′s significance in controlling gene expression, including that of the prolactin gene, making C/EBP α a vital component in the orchestration of various physiological processes.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-C/EBP α Antibody (G-10) has 30 citations in a variety of scientific publications.

Primary antibodies like Anti-C/EBP α Antibody (G-10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

C/EBP α Antibody (G-10) Specifications

Alternate Product Name: C/EBP alpha

Product Clone Name: G-10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: C/EBP α

Epitope Species: human

Product Reactivity/Detection: C/EBP α p42

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 30 citations in various scientific publications

Available Conjugates/Forms for C/EBP α Antibody (G-10): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin, X: TransCruz Reagent

The preferred C/EBP α antibody is C/EBP α Antibody (D-5): sc-365318.