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CREB Antibodies

Santa Cruz Biotechnology features a diverse variety of CREB Antibodies for investigating cAMP response element-binding protein (CREB) in cellular processes. CREB Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CREB functions as a transcription factor that regulates gene expression in response to cellular signals, playing a vital role in processes such as neuronal plasticity, memory formation, and cell survival. CREB dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders, making it an important target for therapeutic intervention. Understanding CREB's molecular mechanisms and signaling pathways is essential for advancing research in neuroscience, oncology, and cellular biology. Researchers can utilize specific monoclonal antibodies to detect and analyze CREB expression, phosphorylation states, and protein interactions. Advanced research tools enable precise investigation of CREB's role in both normal physiological conditions and disease states. Exploring CREB's functions through immunological techniques contributes significantly to understanding cellular signaling networks and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies for CREB research support scientists in making meaningful discoveries that advance our understanding of human health and disease.

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CREB Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CREB1 Antibody (D-12)

sc-377154mouse IgG2a κ254-327 (h)WB, IP, IF, IHC(P), ELISAm, r, h
59
(25)

CREB1 Antibody (24H4B)

sc-271mouse IgG2b κ254-327 (h)WB, IP, IFm, r, h
101
(14)

CREB1 Antibody (X-12)

sc-240mouse IgG1 κ254-327 (h)WB, IP, IFm, r, h
88
(7)

CREB1 Antibody (D-4)

sc-374227mouse IgG2a κ1-341 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(4)

ATF4 Antibody (B-3)

sc-390063mouse IgG2b κ1-290 (h)WB, IP, IF, IHC(P), ELISAm, r, h
112
(31)

Phospho-Specific CREB Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-CREB1 Antibody (10E9)

sc-81486mouse IgG1 κSer 133 (h)WB, IPm, r, h and canine
82
(21)

CREB CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CREB1 CRISPR/Cas9 KO Plasmid (h)

sc-400160hGene KnockoutGFP0
(0)

CREB1 HDR Plasmid (h)

sc-400160-HDRhHomology Directed RepairPuromycin0
(0)

CREB1 Double Nickase Plasmid (h)

sc-400160-NIChGene KnockoutPuromycin0
(0)

CREB1 Double Nickase Plasmid (h2)

sc-400160-NIC-2hGene KnockoutPuromycin0
(0)

CREB1 CRISPR/Cas9 KO Plasmid (m)

sc-419795mGene KnockoutGFP0
(0)

CREB1 HDR Plasmid (m)

sc-419795-HDRmHomology Directed RepairPuromycin0
(0)

CREB1 Double Nickase Plasmid (m)

sc-419795-NICmGene KnockoutPuromycin0
(0)

CREB1 Double Nickase Plasmid (m2)

sc-419795-NIC-2mGene KnockoutPuromycin0
(0)

CREBL2 CRISPR/Cas9 KO Plasmid (h)

sc-410743hGene KnockoutGFP0
(0)

CREBL2 HDR Plasmid (h)

sc-410743-HDRhHomology Directed RepairPuromycin0
(0)

CREBL2 Double Nickase Plasmid (h)

sc-410743-NIChGene KnockoutPuromycin0
(0)

CREBL2 Double Nickase Plasmid (h2)

sc-410743-NIC-2hGene KnockoutPuromycin0
(0)

CREBL2 CRISPR/Cas9 KO Plasmid (m)

sc-433172mGene KnockoutGFP0
(0)

CREBL2 HDR Plasmid (m)

sc-433172-HDRmHomology Directed RepairPuromycin0
(0)

CREBL2 Double Nickase Plasmid (m)

sc-433172-NICmGene KnockoutPuromycin0
(0)

CREBL2 Double Nickase Plasmid (m2)

sc-433172-NIC-2mGene KnockoutPuromycin0
(0)

ATF4 CRISPR/Cas9 KO Plasmid (h2)

sc-400155-KO-2hGene KnockoutGFP
1
(0)

ATF4 HDR Plasmid (h2)

sc-400155-HDR-2hHomology Directed RepairPuromycin
1
(0)

ATF4 Double Nickase Plasmid (h)

sc-400155-NIChGene KnockoutPuromycin
1
(0)

ATF4 Double Nickase Plasmid (h2)

sc-400155-NIC-2hGene KnockoutPuromycin
1
(0)

ATF4 Double Nickase Plasmid (m)

sc-419228-NICmGene KnockoutPuromycin
1
(0)

ATF4 Double Nickase Plasmid (m2)

sc-419228-NIC-2mGene KnockoutPuromycin
1
(0)

CREB CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CREB1 CRISPR Activation Plasmid (h)

sc-400160-ACThGene ActivationPuro, Blast, Hygro0
(0)

CREB1 CRISPR Activation Plasmid (h2)

sc-400160-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CREB1 Lentiviral Activation Particles (h)

sc-400160-LAChGene ActivationPuro, Blast, Hygro0
(0)

CREB1 Lentiviral Activation Particles (h2)

sc-400160-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CREB1 CRISPR Activation Plasmid (m)

sc-419795-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CREB1 CRISPR Activation Plasmid (m2)

sc-419795-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CREB1 Lentiviral Activation Particles (m)

sc-419795-LACmGene ActivationPuro, Blast, Hygro0
(0)

CREB1 Lentiviral Activation Particles (m2)

sc-419795-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 CRISPR Activation Plasmid (h)

sc-410743-ACThGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 CRISPR Activation Plasmid (h2)

sc-410743-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 Lentiviral Activation Particles (h)

sc-410743-LAChGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 Lentiviral Activation Particles (h2)

sc-410743-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 CRISPR Activation Plasmid (m)

sc-433172-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 CRISPR Activation Plasmid (m2)

sc-433172-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 Lentiviral Activation Particles (m)

sc-433172-LACmGene ActivationPuro, Blast, Hygro0
(0)

CREBL2 Lentiviral Activation Particles (m2)

sc-433172-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ATF4 CRISPR Activation Plasmid (h)

sc-400155-ACThGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 CRISPR Activation Plasmid (h2)

sc-400155-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 Lentiviral Activation Particles (h)

sc-400155-LAChGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 Lentiviral Activation Particles (h2)

sc-400155-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 CRISPR Activation Plasmid (m)

sc-419228-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 CRISPR Activation Plasmid (m2)

sc-419228-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 Lentiviral Activation Particles (m)

sc-419228-LACmGene ActivationPuro, Blast, Hygro
1
(0)

ATF4 Lentiviral Activation Particles (m2)

sc-419228-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

CREB siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CREB1 siRNA (h)

sc-29281hGene SilencingN/A
30
(0)

CREB1 shRNA Plasmid (h)

sc-29281-SHhGene SilencingPuromycin
30
(0)

CREB1 shRNA (h) Lentiviral Particles

sc-29281-VhGene SilencingPuromycin
30
(0)

CREB1 siRNA (m)

sc-35111mGene SilencingN/A
19
(2)

CREB1 shRNA Plasmid (m)

sc-35111-SHmGene SilencingPuromycin
19
(2)

CREB1 shRNA (m) Lentiviral Particles

sc-35111-VmGene SilencingPuromycin
19
(2)

CREB1 siRNA (r)

sc-72030rGene SilencingN/A
11
(0)

CREB1 shRNA Plasmid (r)

sc-72030-SHrGene SilencingPuromycin
11
(0)

CREB1 shRNA (r) Lentiviral Particles

sc-72030-VrGene SilencingPuromycin
11
(0)

CREB1 siRNA (chicken)

sc-270089avianGene SilencingN/A
1
(0)

CREB1 shRNA Plasmid (chicken)

sc-270089-SHchickenGene SilencingPuromycin
1
(0)

CREB1 shRNA (chicken) Lentiviral Particles

sc-270089-VchickenGene SilencingPuromycin
1
(0)

CREB1 siRNA (bovine)

sc-270642bovineGene SilencingN/A0
(0)

CREB1 shRNA Plasmid (bovine)

sc-270642-SHbovineGene SilencingN/A0
(0)

CREB1 shRNA (bovine) Lentiviral Particles

sc-270642-VbovineGene SilencingN/A0
(0)

CREBL2 siRNA (h)

sc-96241hGene SilencingN/A0
(0)

CREBL2 shRNA Plasmid (h)

sc-96241-SHhGene SilencingPuromycin0
(0)

CREBL2 shRNA (h) Lentiviral Particles

sc-96241-VhGene SilencingPuromycin0
(0)

CREBL2 siRNA (m)

sc-142564mGene SilencingN/A0
(0)

CREBL2 shRNA Plasmid (m)

sc-142564-SHmGene SilencingPuromycin0
(0)

CREBL2 shRNA (m) Lentiviral Particles

sc-142564-VmGene SilencingPuromycin0
(0)

ATF4 siRNA (h)

sc-35112hGene SilencingN/A
72
(0)

ATF4 shRNA Plasmid (h)

sc-35112-SHhGene SilencingPuromycin
72
(0)

ATF4 shRNA (h) Lentiviral Particles

sc-35112-VhGene SilencingPuromycin
72
(0)

ATF4 siRNA (m)

sc-35113mGene SilencingN/A
17
(0)

ATF4 shRNA Plasmid (m)

sc-35113-SHmGene SilencingPuromycin
17
(0)

ATF4 shRNA (m) Lentiviral Particles

sc-35113-VmGene SilencingPuromycin
17
(0)

CREB Oligonucleotides

Empty Table HeaderProduct NameCONSENSUS CAT. #MUTANT CAT. #MUTANT CONSENSUSBINDING MOTIFCitationsRATING

CREB consensus oligonucleotide

sc-2504sc-25175’-AGA GAT TGC CTG ACG TCA GAG AGC TAG-3’"AC"→"TG"
116
(1)