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IRAK Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of IRAK Antibodies for research focused on interleukin-1 receptor-associated kinase (IRAK) in cellular processes. IRAK Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IRAK proteins function as essential mediators in signaling pathways of the immune response, particularly in Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling. The activation of downstream signaling cascades leads to pro-inflammatory cytokine production, influencing both innate and adaptive immunity. IRAK signaling research continues to reveal new insights about immune regulation and potential therapeutic targets in inflammatory diseases. Investigating IRAK proteins has become increasingly important for understanding autoimmune disorders and developing targeted treatments. Current research focuses on mapping IRAK signaling networks and their impact on cellular responses. Understanding IRAK function helps advance knowledge of immune system regulation and inflammatory disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of IRAK proteins and their role in human health.

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IRAK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IRAK-1 Antibody (F-4)

sc-5288mouse IgG1 κ440-712 (h)WB, IP, IF, IHC(P), ELISAm, r, h
79
(14)

IRAK-1 Antibody (C-2)

sc-5287mouse IgG2a κ440-712 (h)WB, IP, IF, IHC(P), ELISAh
8
(6)

IRAK-1 Antibody (B-5)

sc-55530mouse IgG2b κ440-712 (h)WB, IP, IF, ELISAh
6
(6)

IRAK-1 Antibody (B-8)

sc-515499mouse IgG2a692-712 (h)WB, IP, IF, ELISAh

new

(2)

IRAK-1 Antibody (E-5)

sc-515512mouse IgG1689-712 (h)WB, IP, IF, ELISAm, r, h
1
(2)

IRAK-2 Antibody (D-8)

sc-515885mouse IgG2b κ1-112 (h)WB, IP, IF, IHC(P), ELISAh

new

(1)

IRAK-2 Antibody (R-Q6)

sc-100388mouse IgG1 κ111-210 (h)WB, IP, IF, IHC(P), ELISAh

new

(2)

IRAK-4 Antibody (G-2)

sc-374349mouse IgG2a κ1-100 (h)WB, IP, IF, IHC(P), ELISAh
3
(9)

IRAK-4 Antibody (5-RY38)

sc-134368mouse IgG1 κ1-130 (h)WB, IP, ELISAh
1
(1)

IRAK-M Antibody (XX-6)

sc-100389mouse IgG1 κ497-596 (h)WB, IP, ELISAh
2
(4)

IRAK CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRAK-M CRISPR/Cas9 KO Plasmid (h2)

sc-403219-KO-2hGene KnockoutGFP0
(0)

IRAK-M HDR Plasmid (h2)

sc-403219-HDR-2hHomology Directed RepairPuromycin0
(0)

IRAK-M Double Nickase Plasmid (h)

sc-403219-NIChGene KnockoutPuromycin0
(0)

IRAK-M Double Nickase Plasmid (h2)

sc-403219-NIC-2hGene KnockoutPuromycin0
(0)

IRAK-M CRISPR/Cas9 KO Plasmid (m2)

sc-428667-KO-2mGene KnockoutGFP0
(0)

IRAK-M Double Nickase Plasmid (m)

sc-428667-NICmGene KnockoutPuromycin0
(0)

IRAK-M Double Nickase Plasmid (m2)

sc-428667-NIC-2mGene KnockoutPuromycin0
(0)

IRAK-1 CRISPR/Cas9 KO Plasmid (h)

sc-400264hGene KnockoutGFP
1
(0)

IRAK-1 HDR Plasmid (h)

sc-400264-HDRhHomology Directed RepairPuromycin
1
(0)

IRAK-1 Double Nickase Plasmid (h)

sc-400264-NIChGene KnockoutPuromycin
1
(0)

IRAK-1 Double Nickase Plasmid (h2)

sc-400264-NIC-2hGene KnockoutPuromycin
1
(0)

IRAK-1 CRISPR/Cas9 KO Plasmid (m)

sc-421100mGene KnockoutGFP0
(0)

IRAK-1 Double Nickase Plasmid (m)

sc-421100-NICmGene KnockoutPuromycin0
(0)

IRAK-1 Double Nickase Plasmid (m2)

sc-421100-NIC-2mGene KnockoutPuromycin0
(0)

IRAK-2 CRISPR/Cas9 KO Plasmid (h)

sc-404304hGene KnockoutGFP0
(0)

IRAK-2 HDR Plasmid (h)

sc-404304-HDRhHomology Directed RepairPuromycin0
(0)

IRAK-2 Double Nickase Plasmid (h)

sc-404304-NIChGene KnockoutPuromycin0
(0)

IRAK-2 Double Nickase Plasmid (h2)

sc-404304-NIC-2hGene KnockoutPuromycin0
(0)

IRAK-2 CRISPR/Cas9 KO Plasmid (m)

sc-430883mGene KnockoutGFP0
(0)

IRAK-2 HDR Plasmid (m)

sc-430883-HDRmHomology Directed RepairPuromycin0
(0)

IRAK-2 Double Nickase Plasmid (m)

sc-430883-NICmGene KnockoutPuromycin0
(0)

IRAK-2 Double Nickase Plasmid (m2)

sc-430883-NIC-2mGene KnockoutPuromycin0
(0)

IRAK-4 CRISPR/Cas9 KO Plasmid (h)

sc-416405hGene KnockoutGFP
1
(0)

IRAK-4 HDR Plasmid (h)

sc-416405-HDRhHomology Directed RepairPuromycin
1
(0)

IRAK-4 Double Nickase Plasmid (h)

sc-416405-NIChGene KnockoutPuromycin
1
(0)

IRAK-4 Double Nickase Plasmid (h2)

sc-416405-NIC-2hGene KnockoutPuromycin
1
(0)

IRAK-4 CRISPR/Cas9 KO Plasmid (m)

sc-435222mGene KnockoutGFP0
(0)

IRAK-4 HDR Plasmid (m)

sc-435222-HDRmHomology Directed RepairPuromycin0
(0)

IRAK-4 Double Nickase Plasmid (m)

sc-435222-NICmGene KnockoutPuromycin0
(0)

IRAK-4 Double Nickase Plasmid (m2)

sc-435222-NIC-2mGene KnockoutPuromycin0
(0)

IRAK CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRAK-M CRISPR Activation Plasmid (h)

sc-403219-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M CRISPR Activation Plasmid (h2)

sc-403219-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M Lentiviral Activation Particles (h)

sc-403219-LAChGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M Lentiviral Activation Particles (h2)

sc-403219-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M CRISPR Activation Plasmid (m)

sc-428667-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M CRISPR Activation Plasmid (m2)

sc-428667-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M Lentiviral Activation Particles (m)

sc-428667-LACmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-M Lentiviral Activation Particles (m2)

sc-428667-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-1 CRISPR Activation Plasmid (h)

sc-400264-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-1 CRISPR Activation Plasmid (h2)

sc-400264-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-1 Lentiviral Activation Particles (h)

sc-400264-LAChGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-1 Lentiviral Activation Particles (h2)

sc-400264-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-1 CRISPR Activation Plasmid (m)

sc-421100-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-1 CRISPR Activation Plasmid (m2)

sc-421100-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-1 Lentiviral Activation Particles (m)

sc-421100-LACmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-1 Lentiviral Activation Particles (m2)

sc-421100-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 CRISPR Activation Plasmid (h)

sc-404304-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 CRISPR Activation Plasmid (h2)

sc-404304-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 Lentiviral Activation Particles (h)

sc-404304-LAChGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 Lentiviral Activation Particles (h2)

sc-404304-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 CRISPR Activation Plasmid (m)

sc-430883-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 CRISPR Activation Plasmid (m2)

sc-430883-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 Lentiviral Activation Particles (m)

sc-430883-LACmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-2 Lentiviral Activation Particles (m2)

sc-430883-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-4 CRISPR Activation Plasmid (h)

sc-416405-ACThGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-4 CRISPR Activation Plasmid (h2)

sc-416405-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-4 Lentiviral Activation Particles (h)

sc-416405-LAChGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-4 Lentiviral Activation Particles (h2)

sc-416405-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

IRAK-4 CRISPR Activation Plasmid (m)

sc-435222-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-4 CRISPR Activation Plasmid (m2)

sc-435222-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK-4 Lentiviral Activation Particles (m)

sc-435222-LACmGene ActivationPuro, Blast, Hygro0
(0)

IRAK-4 Lentiviral Activation Particles (m2)

sc-435222-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

IRAK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IRAK-M siRNA (h)

sc-39098hGene SilencingN/A
3
(1)

IRAK-M shRNA Plasmid (h)

sc-39098-SHhGene SilencingPuromycin
3
(1)

IRAK-M shRNA (h) Lentiviral Particles

sc-39098-VhGene SilencingPuromycin
3
(1)

IRAK-M siRNA (m)

sc-146282mGene SilencingN/A
4
(0)

IRAK-M shRNA Plasmid (m)

sc-146282-SHmGene SilencingPuromycin
4
(0)

IRAK-M shRNA (m) Lentiviral Particles

sc-146282-VmGene SilencingPuromycin
4
(0)

IRAK-1 siRNA (h)

sc-35704hGene SilencingN/A
7
(0)

IRAK-1 shRNA Plasmid (h)

sc-35704-SHhGene SilencingPuromycin
7
(0)

IRAK-1 shRNA (h) Lentiviral Particles

sc-35704-VhGene SilencingPuromycin
7
(0)

IRAK-1 siRNA (m)

sc-35705mGene SilencingN/A
6
(0)

IRAK-1 shRNA Plasmid (m)

sc-35705-SHmGene SilencingPuromycin
6
(0)

IRAK-1 shRNA (m) Lentiviral Particles

sc-35705-VmGene SilencingPuromycin
6
(0)

IRAK-1 siRNA (r)

sc-270326rGene SilencingN/A
1
(0)

IRAK-1 shRNA Plasmid (r)

sc-270326-SHrGene SilencingPuromycin
1
(0)

IRAK-1 shRNA (r) Lentiviral Particles

sc-270326-VrGene SilencingPuromycin
1
(0)

IRAK-2 siRNA (h)

sc-106916hGene SilencingN/A0
(0)

IRAK-2 shRNA Plasmid (h)

sc-106916-SHhGene SilencingPuromycin0
(0)

IRAK-2 shRNA (h) Lentiviral Particles

sc-106916-VhGene SilencingPuromycin0
(0)

IRAK-2 siRNA (m)

sc-146281mGene SilencingN/A
2
(0)

IRAK-2 shRNA Plasmid (m)

sc-146281-SHmGene SilencingPuromycin
2
(0)

IRAK-2 shRNA (m) Lentiviral Particles

sc-146281-VmGene SilencingPuromycin
2
(0)

IRAK-4 siRNA (h)

sc-45400hGene SilencingN/A
1
(0)

IRAK-4 shRNA Plasmid (h)

sc-45400-SHhGene SilencingPuromycin
1
(0)

IRAK-4 shRNA (h) Lentiviral Particles

sc-45400-VhGene SilencingPuromycin
1
(0)

IRAK-4 siRNA (m)

sc-45401mGene SilencingN/A
3
(0)

IRAK-4 shRNA Plasmid (m)

sc-45401-SHmGene SilencingPuromycin
3
(0)

IRAK-4 shRNA (m) Lentiviral Particles

sc-45401-VmGene SilencingPuromycin
3
(0)