PLEKHN1 Antibody (D-11): sc-390657
- PLEKHN1 Antibody (D-11) is a mouse monoclonal IgG2a κ PLEKHN1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 621-642 near the C-terminus of PLEKHN1 isoforms 1-3 of human origin
- PLEKHN1 Antibody (D-11) is recommended for detection of PLEKHN1 isoforms 1-3 of human origin by WB, IP, IF and ELISA
- Anti-PLEKHN1 Antibody (D-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PLEKHN1 (D-11): sc-390657.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PLEKHN1 Antibody (D-11) for WB applications. These reagents are now offered in bundles with PLEKHN1 Antibody (D-11) (see ordering information below).
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SEE ALSO...
PLEKHN1 Antibody (D-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects PLEKHN1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PLEKHN1 (D-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PLEKHN1, or pleckstrin homology domain containing, family N member 1, is a 663 amino acid phosphoprotein characterized by the presence of two pleckstrin homology (PH) domains, which are crucial for its role in cellular signaling and membrane trafficking. PLEKHN1 is predominantly located in the cytoplasm and is involved in various cellular processes, including cytoskeletal organization and cell signaling pathways. Proper functioning of PLEKHN1 is essential for maintaining cellular integrity and communication, and dysregulation has been implicated in several diseases, including cancer and neurodegenerative disorders. PLEKHN1 is encoded by a gene located on human chromosome 1p36.33, a region associated with numerous genetic disorders and diseases, highlighting the significance of studying PLEKHN1 in human health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PLEKHN1 Antibody (D-11) References:
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. | McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence. | Meza-Zepeda, LA., et al. 2008. J Cell Mol Med. 12: 553-63. PMID: 18419597
- Gene expression profiling in familial adenomatous polyposis adenomas and desmoid disease. | Bowden, NA., et al. 2007. Hered Cancer Clin Pract. 5: 79-96. PMID: 19725988
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PLEKHN1 Antibody (D-11) | sc-390657 | 200 µg/ml | $316.00 | |||
PLEKHN1 Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-530216 | 200 µg Ab; 10 µg BP | $354.00 | |||
PLEKHN1 Antibody (D-11): m-IgGκ BP-HRP Bundle | sc-523622 | 200 µg Ab, 40 µg BP | $354.00 | |||
PLEKHN1 Antibody (D-11): m-IgG2a BP-HRP Bundle | sc-547459 | 200 µg Ab; 10 µg BP | $354.00 | |||
PLEKHN1 Antibody (D-11) AC | sc-390657 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PLEKHN1 Antibody (D-11) HRP | sc-390657 HRP | 200 µg/ml | $316.00 | |||
PLEKHN1 Antibody (D-11) FITC | sc-390657 FITC | 200 µg/ml | $330.00 | |||
PLEKHN1 Antibody (D-11) PE | sc-390657 PE | 200 µg/ml | $343.00 | |||
PLEKHN1 Antibody (D-11) Alexa Fluor® 488 | sc-390657 AF488 | 200 µg/ml | $357.00 | |||
PLEKHN1 Antibody (D-11) Alexa Fluor® 546 | sc-390657 AF546 | 200 µg/ml | $357.00 | |||
PLEKHN1 Antibody (D-11) Alexa Fluor® 594 | sc-390657 AF594 | 200 µg/ml | $357.00 | |||
PLEKHN1 Antibody (D-11) Alexa Fluor® 647 | sc-390657 AF647 | 200 µg/ml | $357.00 | |||
PLEKHN1 Antibody (D-11) Alexa Fluor® 680 | sc-390657 AF680 | 200 µg/ml | $357.00 | |||
PLEKHN1 Antibody (D-11) Alexa Fluor® 790 | sc-390657 AF790 | 200 µg/ml | $357.00 | |||
PLEKHN1 (D-11) Neutralizing Peptide | sc-390657 P | 100 µg/0.5 ml | $68.00 |