IL-1α Antibody (B-7): sc-9983
- IL-1α Antibody (B-7) is a mouse monoclonal IgG2b κ, cited in 31 publications, provided at 200 µg/ml
- raised against amino acids 113-271 representing mature IL-1α of human origin
- IL-1 alpha Antibody (B-7) is recommended for detection of IL-1α of human origin by WB, IP, IF and IHC(P)
- Anti-IL-1 alpha Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of IL-1α (B-7): sc-9983.
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for IL-1α Antibody (B-7) for WB and IHC(P) applications. These reagents are now offered in bundles with IL-1α Antibody (B-7) (see ordering information below).
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IL-1α Antibody (B-7) is a mouse monoclonal IgG2b kappa light chain antibody that detects IL-1α of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin embedded sections (IHCP). IL-1α Antibody (B-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. IL-1α is a key pro-inflammatory cytokine that plays a vital role in the immune response and inflammation. IL-1α is primarily produced by activated macrophages and is crucial for mediating the body′s response to infection and injury. IL-1α is predominantly located in the cytoplasm of cells, where IL-1α is synthesized and stored in an inactive form. Upon cellular activation, IL-1α is released into the extracellular space, where IL-1α can bind to the IL-1 receptor and initiate a cascade of inflammatory responses. This localization allows for rapid release and action during immune challenges, making IL-1α a critical player in the regulation of immune responses, including the activation of T and B lymphocytes and natural killer cells. Dysregulation of IL-1α has been implicated in various pathological conditions, such as rheumatoid arthritis and inflammatory bowel disease, highlighting IL-1α′s importance in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-1α Antibody (B-7) | sc-9983 | 200 µg/ml | $316.00 | |||
IL-1α Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-520574 | 200 µg Ab, 40 µg BP | $354.00 | |||
IL-1α Antibody (B-7): m-IgG2b BP-HRP Bundle | sc-548838 | 200 µg Ab; 10 µg BP | $354.00 | |||
IL-1α Antibody (B-7) AC | sc-9983 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IL-1α Antibody (B-7) HRP | sc-9983 HRP | 200 µg/ml | $316.00 | |||
IL-1α Antibody (B-7) FITC | sc-9983 FITC | 200 µg/ml | $330.00 | |||
IL-1α Antibody (B-7) PE | sc-9983 PE | 200 µg/ml | $343.00 | |||
IL-1α Antibody (B-7) Alexa Fluor® 488 | sc-9983 AF488 | 200 µg/ml | $357.00 | |||
IL-1α Antibody (B-7) Alexa Fluor® 546 | sc-9983 AF546 | 200 µg/ml | $357.00 | |||
IL-1α Antibody (B-7) Alexa Fluor® 594 | sc-9983 AF594 | 200 µg/ml | $357.00 | |||
IL-1α Antibody (B-7) Alexa Fluor® 647 | sc-9983 AF647 | 200 µg/ml | $357.00 | |||
IL-1α Antibody (B-7) Alexa Fluor® 680 | sc-9983 AF680 | 200 µg/ml | $357.00 | |||
IL-1α Antibody (B-7) Alexa Fluor® 790 | sc-9983 AF790 | 200 µg/ml | $357.00 |