TORC3/CRTC3 Antibody

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Immunocytochemistry/ Immunofluorescence: TORC3/CRTC3 Antibody [NBP2-56127] - Staining of human cell line SiHa shows localization to nucleoplasm & cytosol.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Datasheet
Reviews & Publications
Protocols & FAQs
Support & Research

TORC3/CRTC3 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRTC3
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
TORC3/CRTC3 Recombinant Protein Antigen (NBP2-56127PEP)
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Reactivity Notes

Rat 83%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for TORC3/CRTC3 Antibody

  • CREB regulated transcription coactivator 3
  • CRTC3
  • FLJ21868
  • TORC3
  • TORC-3
  • TORC3CREB-regulated transcription coactivator 3
  • Transducer of CREB protein 3
  • transducer of regulated cAMP response element-binding protein (CREB) 3
  • Transducer of regulated cAMP response element-binding protein 3
  • transducer of regulated CREB protein 3

Background

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMPresponse element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active whendephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 withTAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potentcoactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activationof the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRTC3