c-Fms/CSF-1R Antibody (0.N.178): sc-70451
- c-Fms/CSF-1R Antibody (0.N.178) is a rat monoclonal IgG1 provided at 200 µg/ml
- recommended for detection of c-Fms gp130 and gp150 of mouse, rat and human origin by WB and IP
- See c-Fms/CSF-1R (B-8): sc-46662 for c-Fms/CSF-1R antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for c-Fms/CSF-1R Antibody (0.N.178). This work is in progress.
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c-Fms/CSF-1R Antibody (0.N.178) is a rat monoclonal IgG1 antibody that detects c-Fms/CSF-1R in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). c-Fms/CSF-1R, also known as macrophage colony-stimulating factor receptor (M-CSFR), FIM2, or CD115, is a transmembrane tyrosine kinase receptor that plays a crucial role in the growth and differentiation of myeloid cells. c-Fms/CSF-1R is encoded by the c-Fms proto-oncogene and is predominantly expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells, and certain myoblasts. c-Fms/CSF-1R functions by mediating the actions of macrophage colony-stimulating factor (M-CSF), a glycoprotein essential for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF is also a key player in the inflammatory response, regulating the release of proinflammatory cytokines from macrophages, which underscores its significance in both immune response and tissue homeostasis. anti-c-Fms/CSF-1R antibody (0.N.178) is an invaluable tool for researchers studying myeloid cell biology and the mechanisms underlying inflammation and immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
c-Fms/CSF-1R Antibody (0.N.178) | sc-70451 | 200 µg/ml | $316.00 |