Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 0.5% BSA, 30% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.5 mg/ml
Purity
Affinity purified
Alternate Names for PBR Antibody
benzodiazepine peripheral binding site
BZRPDBI
IBP
MBRPBS
mDRC
Mitochondrial benzodiazepine receptor
PBR
PBRBPBS
PBRS
peripheral benzodiazepine receptor
Peripheral-type benzodiazepine receptor
pk18
PKBSbenzodiazapine receptor (peripheral)
PTBR
translocator protein (18kDa)
translocator protein
TSPO
Background
PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34 kDa voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.
Publications for PBR Antibody (NBP1-45769)(5)
We have publications tested in 3 confirmed species: Human, Mouse, Rat.
We have publications tested in 3 applications: IF/IHC, IHC, IHC-Fr.
FAQs for PBR Antibody (NBP1-45769). (Showing 1 - 1 of 1 FAQs).
I have your PBR antibody, cat# NBP1-45769, which works in immunohistochemistry-Frozen application. Do you have the details of the IHC-Frozen method that was used with this antibody? ..show answer..
I don't see any special conditions noted for this antibody, which means most likely they used our standard IHC-Fr protocol. The antibody will be guaranteed, and should it fail to perform as specified, we would be happy to have the lab provide troubleshooting. If we can't get the product working then we can issue a credit or replacement to resolve the issue.
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