BCL2L10 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00010017-A01	Applications	Species
Guerin JF, Cornut-Thibaut A, Giscard-Destaing S et al. Subcellular dynamics of the maternal cell death regulator BCL2L10 in human preimplantation embryos. Hum Reprod 2013-01-04 [PMID: 23293224]
Guillemin Y, Lalle P, Gillet G et al. Oocytes and early embryos selectively express the survival factor BCL2L10. J Mol Med 2009-06-24 [PMID: 19551325]

Array H00010017-A01

• BCL2L10 Antibodies
• BCL2L10 Proteins