(S)-CPW 399

Catalog #: 1543 Datasheet / COA / SDS

Discontinued Product

1543 has been discontinued.
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(S)-CPW 399 | CAS No. 389888-02-2 | AMPA Receptor Agonists
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Description: Subtype-selective weakly desensitizing AMPA agonist

Chemical Name: (S)-α-Amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-1H-cyclopentapyrimidine-1-propanoic acid

Purity: ≥98%

Product Details
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Biological Activity

Novel subtype-selective and weakly desensitizing AMPA receptor partial agonist (Ki values are 44, 109, 223, 1890 and 2090 nM at GluK1, GluA1, GluA2, GluA3 and GluA4 receptors respectively). Exhibits potent agonist activity at GluA1 and GluA2 subunit-containing AMPA receptors (EC50 values are 24.9 and 13.9 μM respectively) and is excitotoxic in vitro.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data

M.Wt:
239.23
Formula:
C10H13N3O4
Solubility:
Soluble to 50 mM in water
Purity:
≥98%
Storage:
Desiccate at -20°C
CAS No:
389888-02-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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