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Recombinant Human BMP-2 Protein

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Product Details

Summary
Product Discontinued
View other related BMP-2 Peptides and Proteins

Order Details


    • Catalog Number
      P4097
    • Availability
      Product Discontinued

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Recombinant Human BMP-2 Protein Summary

Description
BMP2 (Human) Recombinant Protein

Source: E. coli

Amino Acid Sequence:
Preparation
Method
Escherichia coli expression system
Details of Functionality
The ED50 as determined by the dose-dependent cytolysis of MC3T3-E1 cells is < 50 ng/mL.
Protein/Peptide Type
Recombinant Protein
Gene
BMP2

Applications/Dilutions

Dilutions
  • Functional
  • SDS-Page
Application Notes
This product is useful for and SDS-PAGE and Functional assays.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
No additive Reconstitute with deionized water.
Preservative
No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human BMP-2 Protein

  • BDA2
  • BMP2
  • BMP-2
  • BMP-2A
  • BMP2ABone morphogenetic protein 2A
  • bone morphogenetic protein 2
  • SSFSC

Background

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol BMP2