Anti-HMGA2 antibody

• Supplier: Abcam
• Catalog: ab52039
• Prices: $384.00
• Sizes: 500 µl
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB ICC/IF ICC/IF IHC-P
• Species Reactivities: Mouse, Human
• Antigen: Synthetic peptide corresponding to C-terminal of human HMGA2
• Description: Rabbit Polyclonal
• Gene: HMGA2
• Conjugate: Unconjugated

Product images

Human breast carcinoma stained with Anti-HMGA2 antibody, ab52039 at 1:50 for 30 min at RT

ICC/IF image of ab52039 stained HepG2 cells. The cells were 4% PFA fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab52039, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Product References

WNT10B/beta-catenin signalling induces HMGA2 and proliferation in metastatic - WNT10B/beta-catenin signalling induces HMGA2 and proliferation in metastatic

Wend P, Runke S, Wend K, Anchondo B, Yesayan M, Jardon M, Hardie N, Loddenkemper C, Ulasov I, Lesniak MS, Wolsky R, Bentolila LA, Grant SG, Elashoff D, Lehr S, Latimer JJ, Bose S, Sattar H, Krum SA, Miranda-Carboni GA. EMBO Mol Med. 2013 Feb;5(2):264-79.

Expression of high mobility group A proteins in oral leukoplakia. - Expression of high mobility group A proteins in oral leukoplakia.

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Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer - Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer

Zong Y, Huang J, Sankarasharma D, Morikawa T, Fukayama M, Epstein JI, Chada KK, Witte ON. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3395-404. doi:

Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, - Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,

Mu G, Liu H, Zhou F, Xu X, Jiang H, Wang Y, Qu Y. Hum Pathol. 2010 Apr;41(4):493-502.